Acetyl-Amyloid β-Protein Fragment 15-20 Amide

SIGMA/A6933 - ≥97% (HPLC), powder

Synonym: Ac-QKLVFF-NH₂; amyloid blocker

CAS Number: 189064-06-0
Empirical Formula (Hill Notation): C₄₂H₆₃N₉O₈
Molecular Weight: 822.01
MDL Number: MFCD17215285
Linear Formula: C₄₂H₆₃N₉O₈
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-A6933-1MG	1 mg	$72.80 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
color	white
form	powder
InChI	1S/C42H63N9O8/c1-25(2)22-33(49-38(55)30(18-12-13-21-43)47-39(56)31(46-27(5)52)19-20-35(44)53)41(58)51-36(26(3)4)42(59)50-34(24-29-16-10-7-11-17-29)40(57)48-32(37(45)54)23-28-14-8-6-9-15-28/h6-11,14-17,25-26,30-34,36H,12-13,18-24,43H2,1-5H3,(H2,44,53)(H2,45,54)(H,46,52)(H,47,56)(H,48,57)(H,49,55)(H,50,59)(H,51,58)/t30-,31-,32-,33-,34-,36-/m0/s1
InChI key	DDXTVYDSGCHGAN-PITCCTKHSA-N
Quality Level	200
SMILES string	CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C(N)=O
storage temp.	−20°C
UniProt accession no.	P05067

Amino Acid Sequence:	Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2
Biochem/physiol Actions:	Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.
Packaging:	1 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352202

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