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Ceftazidime hydrate

SIGMA/A6987

Synonym: 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum

CAS Number: 120618-65-7
Empirical Formula (Hill Notation): C22H22N6O7S2 · xH2O
Molecular Weight: 546.58 (anhydrous basis)
MDL Number: MFCD00153936
Linear Formula: C22H22N6O7S2 · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A6987-1G 1 g
 $215.00
1/EA		 Add To Favorites
45-A6987-5G 5 g
 $740.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
assay 95.0-102.0% anhydrous basis
description does not contain sodium carbonate
form powder or crystals
InChI 1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1
InChI key NMVPEQXCMGEDNH-TZVUEUGBSA-N
mode of action cell wall synthesis | interferes
Quality Level 200 
SMILES string [H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].CC(C)(ON=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3ccccc3)=C(N2C1=O)C([O-])=O)c4csc(N)n4)C(O)=O
storage temp. 2-8°C
Application: Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies and to select mutant colonies of interest.
Application: Used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions: Cephalosporins, such as ceftazidime , disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.
General description: Broad spectrum antibiotic; third generation cephalosporin
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Symbol GHS08  GHS08
Signal word Danger
Hazard statements H317 - H334
Precautionary statements P261 - P280 - P342 + P311
Hazard Codes Xn
Risk Statements 42/43
Safety Statements 22-36/37-45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 95.0-102.0% anhydrous basis
Storage Temp. 2-8°C
UNSPSC 51284108

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