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Acepromazine maleate

SIGMA/A7111 - ≥98% (HPLC)

Synonym: Acetopromazine maleate salt; 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine maleate salt; Acepromazine maleate salt

CAS Number: 3598-37-6
Empirical Formula (Hill Notation): C19H22N2OS · C4H4O4
Molecular Weight: 442.53
EC Number: 222-748-9
MDL Number: MFCD00082473
Linear Formula: C19H22N2OS · C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A7111-10MG 10 mg
 $195.00
1/EA		 Add To Favorites
45-A7111-50MG 50 mg
 $749.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color yellow
form powder
InChI 1S/C19H22N2OS.C4H4O4/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19;5-3(6)1-2-4(7)8/h4-5,7-10,13H,6,11-12H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key FQRHOOHLUYHMGG-BTJKTKAUSA-N
Quality Level 100 
SMILES string OC(=O)C=C/C(O)=O.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(C)=O
solubility H2O: >10 mg/mL
storage condition protect from light
storage temp. room temp
Application: Acepromazine maleate has been used:
• as a component of anesthesia cocktail to test its effects on behavioral changes in rats
• as a component of anesthesia cocktail to study its effects on lung resistance of rats
• as an anti-psychotic pharmaceutical agent to study its cytotoxic effects on malignant glioma in glioblastoma (GBM) cells
Biochem/physiol Actions: Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine (#C8138). The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.
Biochem/physiol Actions: Atypical neuroleptic.
Features and Benefits: This compound is featured on the Dopamine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 10, 50 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301 - H336
Precautionary statements P301 + P310 + P330
Hazard Codes Xn
Risk Statements 20/21/22
Safety Statements 22-26-36/37/39
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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