Adenosine, periodate oxidized
SIGMA/A7154 - ≥93%
Synonym: ADOX; Adenosine-2′,3′-dialdehyde
CAS Number: 34240-05-6
Empirical Formula (Hill Notation): C10H11N5O4
Molecular Weight: 265.23
MDL Number: MFCD00056960
Linear Formula: C10H11N5O4
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A7154-100MG
| assay | ≥93% |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C10H11N5O4/c11-9-8-10( |
| InChI key | ILMNSCQOSGKTNZ-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | Nc1ncnc2n(cnc12)C(OC(CO)C |
| solubility | 0.2 M HCl: 50 mg/mL, clear, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | Adenosine, periodate oxidized has been used: • as a methylarginine transferase inhibitor in the human embryonic kidney (HEK)-293 T cells • as a methylase inhibitor in H4 neuroglioma • as a broad inhibitor of S-adenosylmethionine (AdoMet)-dependent methyltransferases in mouse embryo fibroblast NIH3T3 cells |
| Biochem/physiol Actions: | Adenosine, periodate oxidized (Adox) is a protein arginine methyltransferases (PRMTs) inhibitor. It also inhibits the enzyme S-adenosylhomocysteine hydrolase and induces apoptosis. Its inhibitory effect on histone methyltransferases prevents histone methylation. Adox also elicits intrinsic cytotoxic properties. |
| Packaging: | 25, 100 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥93% |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |