L-Aspartic acid
SIGMA/A7219 - from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
Synonym: (S)-(+)-Aminosuccinic acid; (S)-Aminobutanedioic acid
CAS Number: 56-84-8
Empirical Formula (Hill Notation): C4H7NO4
Molecular Weight: 133.10
EC Number: 200-291-6
MDL Number: MFCD00002616
Linear Formula: HO2CCH2CH(NH2)CO2H
Product Type: Chemical
| agency | meets EP testing specifications |
| meets USP testing specifications | |
| assay | 98.5-101.0% |
| biological source | non-animal source |
| color | white to off-white |
| form | powder |
| impurities | endotoxin, tested |
| InChI | 1S/C4H7NO4/c5-2(4(8)9)1-3 |
| InChI key | CKLJMWTZIZZHCS-REOHCLBHSA |
| mp | >300 °C (dec.) (lit.) |
| Quality Level | 300 ![]() |
| SMILES string | N[C@@H](CC(O)=O)C(O)=O |
| solubility | 1 M HCl: 100 mg/mL |
| technique(s) | cell culture | mammalian: suitable |
| Application: | L-Aspartic acid has been used: • as an aspartame (ASP) metabolite to determine acetylcholinesterase (AChE) activity in the hippocampal homogenate of suckling rats • as printed chemotaxis ligands to screen chemotaxis receptors with high-throughput technologies and verify the interactions with surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR) • as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) for supplementation assays of various cultured cell lines |
| Biochem/physiol Actions: | Principal neurotransmitter for fast synaptic excitation. |
| General description: | Aspartic acid(ASP)/aspartate, a non-essential amino acid, is naturally produced by mammals. ASP is one of the 20 building-block amino acids of proteins and has a one letter code, D. L-Aspartic acid can be manufactured industrially by an enzymatic process using the aspartase enzyme. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 98.5-101.0% |
| mp | >300 °C (dec.) (lit.) |
| UNSPSC | 12352209 |

