Albumin human
SIGMA/A7223 - recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE)
Synonym: Albagen™; rHSA
CAS Number: 70024-90-7
Empirical Formula (Hill Notation): C2936H4624N786O889S41
Molecular Weight: 66471.53
MDL Number: MFCD00081418
Linear Formula: C2936H4624N786O889S41
Product Type: Chemical
assay | ≥90% (SDS-PAGE) |
biological source | human |
concentration | 5% in aqueous buffer |
form | solution |
InChI | 1S/C3F8/c4-1(5,2(6,7)8)3( |
InChI key | QYSGYZVSCZSLHT-UHFFFAOYSA |
mol wt | monomer ~67 kDa |
Quality Level | 200 |
recombinant | expressed in Pichia pastoris |
shipped in | wet ice |
storage temp. | 2-8°C |
technique(s) | cell culture | mammalian: suitable |
UniProt accession no. | P02768 |
Application: | This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells. |
Biochem/physiol Actions: | Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood. |
Legal Information: | Albagen is a trademark of Albumin Therapeutics, LLC. |
Other Notes: | View more information on human serum albumin . |
Physical form: | Solution in phosphate buffered saline containing 4 mM sodium caprylate and 4 mM N-acetyltryptophan. |
Physical properties: | Recombinant construct with N-terminal deletion of Asp. Structurally equivalent to native albumin by x-ray crystallography. The N-terminal Asp is the principal Cu2+ and Ni2+ chelation site; its deletion eliminates an important antigenic determinant, and the protein is hypoallergenic. Also blocked at Cys34 to improve stability, monomer content and homogeneity. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥90% (SDS-PAGE) |
Storage Temp. | 2-8°C |
UNSPSC | 12352202 |