Azelastine hydrochloride

SIGMA/A7611 - ≥98% (HPLC)

Synonym: 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one hydrochloride; Astelin; Optivar

CAS Number: 79307-93-0
Empirical Formula (Hill Notation): C₂₂H₂₄ClN₃O · HCl
Molecular Weight: 418.36
MDL Number: MFCD00242783
Linear Formula: C₂₂H₂₄ClN₃O · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A7611-10MG	10 mg	$82.10 1/EA	Add To Favorites
45-A7611-50MG	50 mg	$326.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to off-white
form	powder
InChI	1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
InChI key	YEJAJYAHJQIWNU-UHFFFAOYSA-N
originator	Wallace
Quality Level	100
SMILES string	Cl.CN1CCCC(CC1)N2N=C(Cc3ccc(Cl)cc3)c4ccccc4C2=O
solubility	DMSO: >10 mg/mL
storage condition	desiccated
storage temp.	−20°C

Application:	Azelastine hydrochloride is a H1 histamine receptor antagonist and NF-kB activator. Azelastine hydrochloride has been used in a study to investigate the potential of polymeric microspheres for treatment of allergic conjunctivitis.
Biochem/physiol Actions:	H1 histamine receptor antagonist; NF-kB activator.
Features and Benefits:	This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits:	This compound was developed by Wallace . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	10, 50 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264 - P270 - P301 + P312 - P501
Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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