Aloe-emodin
SIGMA/A7687 - ≥95% (HPLC)
Synonym: 1,8-Dihydroxy 3-
CAS Number: 481-72-1
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
EC Number: 207-571-7
MDL Number: MFCD00017373
Linear Formula: C15H10O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A7687-25MG
| assay | ≥95% (HPLC) |
| biological source | plant root (Rheum palmatum) |
| color | yellow to brown |
| form | powder |
| InChI | 1S/C15H10O5/c16-6-7-4-9-1 |
| InChI key | YDQWDHRMZQUTBA-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | OCc1cc(O)c2C(=O)c3c(O)ccc |
| storage temp. | 2-8°C |
| technique(s) | HPLC: suitable |
| Application: | Aloe-emodin has been used as a standard in high performance liquid chromatography (HPLC) for separation and identification of phenolic compounds in Aloe arborescens Miller var. natalensis Berger (Kidachi aloe). |
| Biochem/physiol Actions: | Aloe-emodin exhibits antibacterial, antiviral, anti-inflammatory and hepatoprotective effects. |
| Biochem/physiol Actions: | Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin. |
| General description: | Aloe-emodin is a hydroxyanthraquinone found naturally in aloe plants. |
| Packaging: | 25 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301 + P312 + P330 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352205 |