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Adenosine 5′-[β-thio]diphosphate trilithium salt

SIGMA/A8016 - ≥80% (HPLC)

Synonym: ADP-β-S; Adenosine-5′-0-(2-thiodiphosphate) trilithium salt; Ado-5′-PP[S]

CAS Number: 73536-95-5
Empirical Formula (Hill Notation): C10H12Li3N5O9P2S
Molecular Weight: 461.07
MDL Number: MFCD00077314
Linear Formula: C10H12Li3N5O9P2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A8016-5MG 5 mg
 $250.00
1/EA		 Add To Favorites
45-A8016-25MG 25 mg
 $834.00
1/EA		 Add To Favorites

 

assay ≥80% (HPLC)
form powder
InChI 1S/C10H15N5O9P2S.3Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-25(18,19)24-26(20,21)27;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H2,20,21,27);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
InChI key CPKFUAYUUSSFFZ-MSQVLRTGSA-K
Quality Level 200 
SMILES string [Li+].[Li+].[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O
storage temp. −20°C
Application: Adenosine 5′-[β-thio]diphosphate is a substrate and inhibitor for AMP dependent enzyme systems. Adenosine 5′-[β-thio]diphosphate has been used to explore the myenteric control mechanisms of human esophageal motility and the effect of nitrergic and nonnitrergic neurotransmitters.
Application: Adenosine 5′-[β-thio]diphosphate trilithium salt has been used to induce neuropathic pain in rats to study the effect of dorsal horn cannabinoid CB2 receptor activation on the expression of P2Y12 and P2Y13 (purinoceptors) receptors.
Biochem/physiol Actions: P2Y receptor agonist.
Features and Benefits: This compound is featured on the P2 Receptors: P2Y G-Protein Family  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: Substrate and inhibitor for AMP dependent enzyme systems.
Other Notes: Non-hydrolyzable ADP analog
Purity ≥80% (HPLC)
Storage Temp. −20°C
UNSPSC 41106305

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