Adenosine 5′-[β-thio]diphosphate trilithium salt
SIGMA/A8016 - ≥80% (HPLC)
Synonym: ADP-β-S; Adenosine-5′-0-(2-thiodiphosphate) trilithium salt; Ado-5′-PP[S]
CAS Number: 73536-95-5
Empirical Formula (Hill Notation): C10H12Li3N5O9P2S
Molecular Weight: 461.07
MDL Number: MFCD00077314
Linear Formula: C10H12Li3N5O9P2S
Product Type: Chemical
assay | ≥80% (HPLC) |
form | powder |
InChI | 1S/C10H15N5O9P2S.3Li/c11- |
InChI key | CPKFUAYUUSSFFZ-MSQVLRTGSA |
Quality Level | 200 ![]() |
SMILES string | [Li+].[Li+].[Li+].Nc1ncnc |
storage temp. | −20°C |
Application: | Adenosine 5′-[β-thio]diphosphate is a substrate and inhibitor for AMP dependent enzyme systems. Adenosine 5′-[β-thio]diphosphate has been used to explore the myenteric control mechanisms of human esophageal motility and the effect of nitrergic and nonnitrergic neurotransmitters. |
Application: | Adenosine 5′-[β-thio]diphosphate trilithium salt has been used to induce neuropathic pain in rats to study the effect of dorsal horn cannabinoid CB2 receptor activation on the expression of P2Y12 and P2Y13 (purinoceptors) receptors. |
Biochem/physiol Actions: | P2Y receptor agonist. |
Features and Benefits: | This compound is featured on the P2 Receptors: P2Y G-Protein Family ![]() ![]() |
Other Notes: | Non-hydrolyzable ADP analog |
Substrates: | Substrate and inhibitor for AMP dependent enzyme systems. |
Symbol | ![]() ![]() |
Signal word | Warning |
Hazard statements | H302 - H371 |
Precautionary statements | P301 + P312 + P330 - P308 + P311 |
Hazard Codes | Xn |
Risk Statements | 20/21/22-68/20/21/22 |
Safety Statements | 36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥80% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |