4-Aminophthalhydrazide
SIGMA/A8264
Synonym: 6-
CAS Number: 3682-14-2
Empirical Formula (Hill Notation): C8H7N3O2
Molecular Weight: 177.16
MDL Number: MFCD00010560
Linear Formula: C8H7N3O2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C8H7N3O2/c9-4-1-2-5-6( |
| InChI key | HUDPLKWXRLNSPC-UHFFFAOYSA |
| mp | 300 °C (lit.) |
| Quality Level | 200  |
| SMILES string | Nc1ccc2C(=O)NNC(=O)c2c1 |
| solubility | 2 M NH4OH: 50 mg/mL, clear to slightly hazy |
| Application: | 4-Aminophthalhydrazide has been used in: • chemiluminescence-based reactive oxygen species (ROS) assay in bone marrow (BM) neutrophils post-Yersinia pseudotuberculosis infection • neutrophil ROS assays post-K. pneumonia exposure • neutrophil ROS assays in response to formylated-methionine-leu |
| Biochem/physiol Actions: | 4-Aminophthalhydrazide or isoluminol is a chemiluminescent compound that comprises a phthalazine ring. It is more hydrophilic than luminol. Isoluminol is commercially used in a wide variety of in vitro immunoassays and is a chemiluminescence amplifier for studying reactive oxygen species. It is also useful as an electroluminescence (ECL) biosensor and as a probe for rapid microbial detection. |
| Features and Benefits: | Produces chemiluminescence. |
| Packaging: | 1, 5, 10 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| mp | 300 °C (lit.) |
| UNSPSC | 12352204 |