L-Asparagine monohydrate
SIGMA/A8381 - ≥99% (TLC)
Synonym: (S)
CAS Number: 5794-13-8
Empirical Formula (Hill Notation): C4H8N2O3 · H2O
Molecular Weight: 150.13
EC Number: 200-735-9
MDL Number: MFCD00151038
Linear Formula: NH2COCH2CH(NH2)COOH · H2O
Product Type: Chemical
| application(s) | cell analysis peptide synthesis |
| assay | ≥99% (TLC) |
| biological source | synthetic |
| color | white to off-white |
| form | powder |
| InChI | 1S/C4H8N2O3.H2O/c5-2(4(8) |
| InChI key | RBMGJIZCEWRQES-DKWTVANSSA |
| mp | 233-235 °C (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | [H]O[H].N[C@@H](CC(N)=O)C |
| Application: | L-Asparagine monohydrate has been used: • as a component of Sauton’s and chelated Sauton’s media for mycobacterial growth • to test its effect in the induction of Ca2+ flux in rice roots using aequorin luminescence imaging • as a component of fermentation medium for the Blakeslea trispora spores |
| Biochem/physiol Actions: | Asparagine has high nitrogen to carbon ratio and is a key regulator for nitrogen storage and transport. Its thermal degradation in the presence of sugars leads to the acrylamide formation in foods. Asparagine serves as an amino acid exchange factor and is essential for amino acid homeostasis. It favors cancer cell proliferation. |
| Biochem/physiol Actions: | L-Asparagine, a proteinogenic amino acid, is used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies and in cell culture based research. |
| General description: | Asparagine biosynthesis is catalyzed by glutamine-dependent asparagine synthetase in mammalian tissues. Elevated levels of free asparagine is observed in plants facing stress in the form of drought or high salt. It is also present in senescing leaves and germinating seeds. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 10, 25, 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (TLC) |
| mp | 233-235 °C (lit.) |
| UNSPSC | 12352209 |

