Amoxicillin
SIGMA/A8523 - 95.0-102.0% anhydrous basis
Synonym: Amoxicillin anhydrous; D-(-)-α-Amino-p-hydroxybenzyl penicillin
CAS Number: 26787-78-0
Empirical Formula (Hill Notation): C16H19N3O5S
Molecular Weight: 365.40
EC Number: 248-003-8
MDL Number: MFCD00056860
Linear Formula: C16H19N3O5S
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| assay | 95.0-102.0% anhydrous basis |
| form | powder |
| InChI | 1S/C16H19N3O5S/c1-16(2)11 |
| InChI key | LSQZJLSUYDQPKJ-NJBDSQKTSA |
| mode of action | cell wall synthesis | interferes |
| Quality Level | 200 ![]() |
| SMILES string | CC1(C)S[C@@H]2[C@H](NC(=O |
| storage temp. | 2-8°C |
| Application: | Amoxicillin is used to study the oxygen dependent antimicrobial systems of polymorphonuclear leukocytes (PMNLs), the risk of resistance development in Helicobacter pylori, and various dosing strategies against Streptococcus pneumoniae and Pneumococcal pneumonia . It is also used to study the synthesis of bacterial cell walls at the level of peptidoglycan polymer chain cross-linking involving bacterial transpeptidase. |
| Biochem/physiol Actions: | Amoxicillin is a broad-spectrum, β-lactam antibiotic. It is a 4-hydroxy analog of ampicillin with similar ranges of actions and utility to ampicillin. Amoxicillin inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. |
| General description: | Chemical structure: ß-lactam |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H317 - H334 |
| Precautionary statements | P261 - P280 - P342 + P311 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 95.0-102.0% anhydrous basis |
| Storage Temp. | 2-8°C |
| UNSPSC | 51102829 |


