Anti-Aflatoxin B1 antibody produced in rabbit
SIGMA/A8679 - fractionated antiserum, buffered aqueous solution
Synonym: Anti-Aflatoxin B1
Product Type: Chemical
ELISA Anti-Aflatoxin B1 antibody produced in Rabbit (Cat. No. A8679), followed by 1:10,000 Anti-Rabbit IgG (whole molecule)-Alkaline Phosphatase antibody produced in Goat (Cat. No. A9919), was serially diluted to detect Aflatoxin B1 by indirect ELISA.
| antibody form | fractionated antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 200  |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | capture ELISA: 1:4,000 using aflatoxin B1-BSA |
| Application: | Rabbit Anti-Aflatoxin B1 antibody has been used for the development of electrochemical immunosensors. The antibody has also been used in designing novel sandwich immunoassays. The product can also be used for capture ELISA at a dilution of 1:1,000. |
| Biochem/physiol Actions: | Aflatoxin B1 and its metabolites act as potent carcinogens, mutagens and teratogens. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Aflatoxin B1 is the most abundant and significant member of the group, which includes B2, B2a, G1, G2a, M1, M2, P1, Q1, aflatoxicol I (natural isomer), aflatoxicol II (unnatural isomer), tetrahydrodeoxy aflatoxin B1, and the unstable reactive B1 (8,9)-epoxide. |
| General description: | Aflatoxins are highly carcinogenic. |
| General description: | Aflatoxins are highly toxic mycotoxins produced by the fungus Aspergillus. Aflatoxins are commonly found in various grains and peanut butter. |
| General description: | Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins. |
| General description: | The antibody reacts with the B1 aflatoxin and also recognizes aflatoxins G1, B2, and the KLH protein. No cross-reaction is observed with aflatoxins and B2a, G2, G2a, M1. |
| Immunogen: | aflatoxin B1-KLH. |
| Physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| Specificity: | Sensitivity range for this product is 0.005-20 ng/ml of aflatoxin B1. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |