Antalarmin hydrochloride
SIGMA/A8727 - ≥98% (HPLC), solid
Synonym: N-
CAS Number: 220953-69-5
Empirical Formula (Hill Notation): C24H34N4·HCl
Molecular Weight: 415.01
MDL Number: MFCD05664721
Linear Formula: C24H34N4·HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | off-white |
form | solid |
InChI | 1S/C24H34N4.ClH/c1-9-11-1 |
InChI key | CGDGXEDXEXACKQ-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | Cl[H].CCCCN(CC)c1nc(C)nc2 |
solubility | DMSO: >10 mg/mL |
storage condition | desiccated |
storage temp. | 2-8°C |
Application: | Antalarmin hydrochloride has been used: • to study its effect on stress-induced tryptophan hydroxylase 2 activity • to study the anxiogenic effects of corticotropin-releasing factor 1 (CRF1) activation • to analyze the therapeutic effect of blocking corticotrophin-releasing hormone (CRH) signaling in treating social stress-induced depression |
Application: | Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist. |
Biochem/physiol Actions: | Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist. |
Biochem/physiol Actions: | Antalarmin serves as a non steroidal inhibitor of pregnancy even during the early stages. It is known to delay parturition. It also prevents the development of gastric ulcers which arises in response to stress. |
Features and Benefits: | This compound is featured on the Corticotropin-Releasing Factor Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Packaging: | 10, 50 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |