Anti-Mouse IgM (μ-chain specific)–Peroxidase antibody produced in goat
SIGMA/A8786 - affinity isolated antibody, buffered aqueous solution
Synonym: Goat Anti-Mouse IgM (μ-chain specific)–HRP
MDL Number: MFCD00162661
Product Type: Chemical
Glioblastoma, a malignant human brain tumor, stained positive for white matter oligodendroglial cells using Anti-GalCer followed by Goat Anti-Mouse IgM-peroxidase conjugate (Cat. No. A8786) and AEC as substrate. Positive staining is on the tumor cell membrane and processes. From J. Li, Ohio State Univ., Columbus, OH.
Mouse brain stained positive for white matter oligodendroglial cells using Anti-GalCer followed by Goat Anti-Mouse IgM-Peroxidase conjugate (Cat. No. A8786) and AEC as substrate. From J. Li, Ohio State Univ., Columbus, OH.
| antibody form | affinity isolated antibody |
| antibody product type | secondary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | peroxidase conjugate |
| form | buffered aqueous solution |
| Quality Level | 200  |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | direct ELISA: 1:10,000 |
| Application: | Anti-Mouse IgM (μ-chain specific)-Peroxidase antibody produced in goat has also been used in: • western blotting • enzyme linked immunosorbent assay (ELISA) • immunohistochemistry |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | IgM is a glycoprotein antibody that regulates humoral immune responses. Mouse IgM is involved in modulating B cell memory . This antibody isotype has also been implicated in the development of autoimmune responses associated with the pathogenesis of type 1 diabetes in mice . Anti-Mouse IgM (μ-chain specific)-Peroxidase antibody is specific for mouse IgM when tested against purified mouse IgA, IgM, and IgG. |
| Immunogen: | Purified mouse IgM |
| Packaging: | 1 mL in glass bottle |
| Physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4 containing 1% bovine serum albumin with preservative. |
| Preparation Note: | Prepared using the periodate method described by Wilson, M.B., and Nakane, P.K., in Immunofluorescence and Related Staining Techniques, Elsevier/North Holland Biomedical Press, Amsterdam, p215 (1978). |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 - H412 |
| Precautionary statements | P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |