Aceclofenac
SIGMA/A8861 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 89796-99-6
Empirical Formula (Hill Notation): C16H13Cl2NO4
Molecular Weight: 354.18
MDL Number: MFCD00864296
Linear Formula: C16H13Cl2NO4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | off-white to light tan |
form | powder |
InChI | 1S/C16H13Cl2NO4/c17-11-5- |
InChI key | MNIPYSSQXLZQLJ-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | OC(=O)COC(=O)Cc1ccccc1Nc2 |
solubility | DMSO: ≥20 mg/mL |
storage temp. | room temp |
Application: | Aceclofenac (ACE) has been used as an internal standard in the in vivo blood-brain barrier assay. It has also been used to study the interaction of ACE with bovine serum albumin (BSA) by using spectroscopic techniques in combination with computational methods. |
Biochem/physiol Actions: | Aceclofenac is a phenyl acetic acid derivative used for treating symptoms like swelling, tenderness, and stiffness due to muscle-skeletal and bone-related diseases (rheumatoid arthritis, juvenile arthritis, osteoarthritis, and acute gouty arthritis). This compound shows analgesic and antipyretic properties. Aceclofenac suppresses prostaglandin biosynthesis. |
Biochem/physiol Actions: | Non-steroidal, anti-inflammatory drug (NSAID), with selectivity for COX-2 over COX-1. |
Packaging: | 10, 50 mg in glass bottle |
Symbol | GHS06,GHS09 |
Signal word | Danger |
Hazard statements | H301 - H319 - H410 |
Precautionary statements | P273 - P301 + P310 + P330 - P305 + P351 + P338 |
Hazard Codes | T,N |
Risk Statements | 25-36-50/53 |
Safety Statements | 26-45-60-61 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | room temp |
UNSPSC | 12352200 |