Adenosine 5′-triphosphate dipotassium salt hydrate
SIGMA/A8937 - from microbial, ≥92% (HPLC)
Synonym: ATP; 5′-ATP-K2
CAS Number: 42373-41-1 (anhydrous)
Empirical Formula (Hill Notation): C10H14K2N5O13P3 · xH2O
Molecular Weight: 583.36 (anhydrous basis)
Linear Formula: C10H14K2N5O13P3 · xH2O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A8937-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A8937-5G
| assay | ≥92% (HPLC) |
| biological source | microbial |
| form | powder |
| Quality Level | 200  |
| SMILES string | [K+].[K+].Nc1ncnc2n(cnc12 |
| solubility | H2O: 50 mg/mL |
| storage temp. | −20°C |
| Application: | Adenosine 5′-triphosphate dipotassium salt hydrate has been used: • in in vitro transcription reaction as nucleotide source and in 2x RNA binding buffer • as a component of energy solution for calibrating crude cell extract • to test its dependency with PK11195 in mediating autophagy |
| Biochem/physiol Actions: | Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. Metabolic disorders lead to ATP deficiency. Use of xanthine oxidoreductase inhibitors and inosine improves intracellular ATP levels. |
| Biochem/physiol Actions: | P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems. |
| Caution: | For maximum stability, store as frozen solution at pH 3.5 to 6.8. |
| General description: | Adenosine 5′-triphosphate (ATP) is synthesized in mitochondria by oxidative phosphorylation. |
| Packaging: | 1, 5 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥92% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |