Adenosine 5′-triphosphate di(tris) salt hydrate

SIGMA/A9062 - ≥95%

Synonym: ATP; 5′-ATP-DiTris

CAS Number: 102047-34-7 (anhydrous)
Empirical Formula (Hill Notation): C₁₀H₁₆N₅O₁₃P₃ · 2C₄H₁₁NO₃ · xH₂O
Molecular Weight: 749.45 (anhydrous basis)
MDL Number: MFCD32695621
Linear Formula: C₁₀H₁₆N₅O₁₃P₃ · 2C₄H₁₁NO₃ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A9062-100MG	100 mg	$47.00 1/EA	Add To Favorites
45-A9062-1G	1 g	$102.00 1/EA	Add To Favorites
45-A9062-5X1G	1 g	$430.00 5/EA	Add To Favorites
45-A9062-10G	10 g	$728.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9062-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
biological source	(Fermentation)
cation traces	Na: ≤0.1%
form	powder
InChI	1S/C10H16N5O13P3.2C4H11NO3.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;25-4(1-6,2-7)3-8;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);26-8H,1-3,5H2;1H2/t4-,6-,7-,10-;;;/m1.../s1
InChI key	ZMNHJZFDZFGOFE-MSQVLRTGSA-N
Quality Level	200
shipped in	dry ice
SMILES string	O.NC(CO)(CO)CO.NC(CO)(CO)CO.Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
solubility	H₂O: 50 mg/mL
storage temp.	−20°C

Application:	Adenosine 5′-triphosphate di(tris) salt hydrate has been used: • to treat cells for Ca²⁺ influx measurements in stromal interaction molecule 1 knockout (STIM1−/−) mice and in vitro chemotaxis assay for microglial migration • supplemented in buffer C for mitochondrial respiratory control assay and complex V activity assay • in the inhibition of silver nano particles (AgNPs) on Na⁺/K⁺-ATPase activity
Biochem/physiol Actions:	Adenosine 5′-triphosphate di(tris) salt dehydrate is useful in applications that require the absence of metals. Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.
Biochem/physiol Actions:	P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems
Disclaimer:	Unstable: For maximum stability, store as frozen solution at pH 3.5 to 6.8.
Packaging:	1, 10 g in poly bottle
Packaging:	100 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	41106305

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