Adenosine 2′:3′-cyclic monophosphate sodium salt

SIGMA/A9376 - ≥93%

Synonym: 2′,3′-cAMP sodium salt

CAS Number: 37063-35-7
Empirical Formula (Hill Notation): C₁₀H₁₁N₅NaO₆P
Molecular Weight: 351.19
EC Number: 253-328-3
MDL Number: MFCD00005757
Linear Formula: C₁₀H₁₁N₅O₆PNa
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A9376-100MG	100 mg	$302.00 1/EA	Add To Favorites
45-A9376-250MG	250 mg	$622.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥93%
biological source	synthetic (organic)
form	powder
InChI	1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7-6(4(1-16)19-10)20-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
InChI key	VSDSIACSNXHGOV-MCDZGGTQSA-M
Quality Level	200
SMILES string	[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H]4OP([O-])(=O)O[C@@H]34
solubility	water: 50 mg/mL, clear, colorless
storage temp.	−20°C

Application:	Adenosine 2′:3′-cyclic monophosphate sodium salt has been used in lysis buffer for affinity purification and also in microscale thermophoresis measurements. It has also been used in electrophysiological studies of Tenebrio tubules.
Biochem/physiol Actions:	Adenosine 2′,3′-cyclic monophosphate (2′,3′-cAMP) is believed to serve as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.
Disclaimer:	Caution: Do not confuse with the common adenosine 2′(3′)-monophosphate (mixed isomers).
Packaging:	100, 250 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥93%
Storage Temp.	−20°C
UNSPSC	41106305

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