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Ammonium chloride

SIGMA/A9434 - for molecular biology, suitable for cell culture, ≥99.5%

Synonym: Salmiac

CAS Number: 12125-02-9
Empirical Formula (Hill Notation): H4ClN
Molecular Weight: 53.49
EC Number: 235-186-4
MDL Number: MFCD00011420
Linear Formula: NH4Cl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-A9434-500G 500 g
$71.80
1/EA
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45-A9434-1KG 1 kg
$98.70
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: A9434-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: A9434-1KG

 

anion traces phosphate (PO43-): ≤2 ppm
  sulfate (SO42-): ≤20 ppm
assay ≥99.5%
cation traces Fe: ≤2 ppm
  heavy metals (as Pb): ≤5 ppm
foreign activity DNase, RNase, protease, none detected
form powder or crystals
grade for molecular biology
InChI 1S/ClH.H3N/h1H;1H3
InChI key NLXLAEXVIDQMFP-UHFFFAOYSA-N
mp 340 °C (subl.) (lit.)
Quality Level 200 
SMILES string N.Cl
technique(s) cell culture | mammalian: suitable
vapor density 1.9 (vs air)
vapor pressure 1 mmHg ( 160.4 °C)
Application: Ammonium chloride has been used:
• as an inhibitor of endosome acidification in vero cells
• as an autophagy inhibitor in vascular smooth muscle cell (VSMC)
• in the depletion and lysis of erythrocytes in testis parenchyma homogenate

Biochem/physiol Actions: Ammonium chloride is one of the three principal components of the nitrogen cycle. Ammonium chloride administration promotes creatinine and urea clearance andinduces metabolic acidosis in mice. Excess of ammonium chloride inhibits Kreb′s pathway in brain and depletes ATP in astrocytes. Ammonium chloride inhibits acidification in the endosome-lysosome system. Ammonium chloride is a hemolysing agent used for the lysis of erythrocytes.
Packaging: 1 kg in poly bottle
Packaging: 500 g in poly bottle
Purity ≥99.5%
mp 340 °C (subl.) (lit.)
UNSPSC 12352302

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