Advanced Search



Adenosine 3′,5′-cyclic monophosphate

SIGMA/A9501 - ≥98.5% (HPLC), powder

Synonym: 3′,5′-Cyclic AMP; Adenosine 3′,5′-cyclophosphate; cAMP

CAS Number: 60-92-4
Empirical Formula (Hill Notation): C10H12N5O6P
Molecular Weight: 329.21
EC Number: 200-492-9
MDL Number: MFCD00005845
Linear Formula: C10H12N5O6P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A9501-1G 1 g
 $295.00
1/EA		 Add To Favorites
45-A9501-5G 5 g
 $1120.00
1/EA		 Add To Favorites
45-A9501-25G 25 g
 $2760.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9501-1G

 

assay ≥98.5% (HPLC)
color white
form powder
InChI 1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChI key IVOMOUWHDPKRLL-KQYNXXCUSA-N
mp 260 °C (dec.) (lit.)
Quality Level 200 
SMILES string Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O
solubility H2O: 10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.)
storage temp. −20°C
Application: Adenosine 3′,5′-cyclic monophosphate has been used:
• as cell culture medium supplement in embryonic spinal neurons
• as a component of ringer solution for perfusion studies
• to induce neuroendocrine differentiation in human lung cancer cell lines
Biochem/physiol Actions: Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
Features and Benefits: This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox  and Cyclic Nucleotide  products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 1, 5, 25 g in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.5% (HPLC)
mp 260 °C (dec.) (lit.)
Storage Temp. −20°C
UNSPSC 41106305

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top