Albumin from human serum
SIGMA/A9511 - lyophilized powder, ≥97% (agarose gel electrophoresis)
Synonym: HSA
CAS Number: 70024-90-7
EC Number: 274-272-6
MDL Number: MFCD00081418
Product Type: Chemical
Human serum albumin is a 66 kDa predominantly monomeric protein with one free sulfhydryl group and 17 intrachain disulfide bonds.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9511-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9511-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9511-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9511-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9511-500MG
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| assay | ≥97% (agarose gel electrophoresis) |
| biological source | human |
| form | lyophilized powder |
| impurities | HIV I and HIVII, HCV and HBsAg, tested negative |
| InChI | 1S/C3F8/c4-1(5,2(6,7)8)3( |
| InChI key | QYSGYZVSCZSLHT-UHFFFAOYSA |
| mol wt | monomer calculated mol wt 66478 Da |
| Quality Level | 300  |
| solubility | H2O: soluble 50 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | ELISA: suitable |
| tissue culture: suitable | |
| western blot: suitable | |
| UniProt accession no. | P02768  |
| Application: | Albumin from human serum has been used: • to standardize the column for molecular-exclusion chromatography • to prepare the tobacco mosaic virus (TMV)-poly ethylene glycol (PEG8)-serum albumin (SA) particles • to analyze its modifications after oxidation using a Fenton system |
| Application: | Albumin-bound fluorescence was used in serum of patients with chronic renal failure. |
| Biochem/physiol Actions: | Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator in liver disease. Oxidative modification of albumin is seen in advanced liver disease. |
| Biochem/physiol Actions: | Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function. |
| Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
| General description: | Albumin is the most copious protein in blood plasma. Liver produces human albumin. |
| General description: | Human albumin possess a molecular weight of 67 kDa. |
| Other Notes: | View more information on human serum albumin . |
| Packaging: | 1, 5, 10, 25 g in poly bottle |
| Packaging: | 100, 500 mg in poly bottle |
| Preparation Note: | Prepared using method IV of Cohn, E.J., et al., J. Am. Chem. Soc., 69, 1753 (1947). |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (agarose gel electrophoresis) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |