Anti-Antithrombin III antibody produced in rabbit
SIGMA/A9522 - fractionated antiserum, lyophilized powder
Synonym: Anti-AT3
MDL Number: MFCD00162398
Product Type: Chemical
ELISA Anti-Antithrombin III antibody produced in Rabbit (Cat. No. A9522), followed by 1:5,000 Anti-Rabbit IgG (whole molecule)-Peroxidase antibody produced in Goat (Cat. No. A0545), was serially diluted to detect Antithrombin III by indirect ELISA.
| antibody form | fractionated antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| packaging | vial of 2 mL lyophilized antiserum |
| Quality Level | 200  |
| species reactivity | human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: 1:25,000 |
| UniProt accession no. | P01008  |
| Application: | Anti-Antithrombin III antibody has been used in western blotting and antigenic assay. |
| Biochem/physiol Actions: | Antithrombin III is a serine protease inhibitor which affects many intrinsic and extrinsic blood coagulation pathways. It inactivates the function of thrombin and factor X in blood. Severe sepsis is caused due to lack of antithrombin III. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Antithrombin III (ATIII) is a small glycoprotein produced by the liver that functions as a serine protease inhibitor to block coagulation. |
| General description: | Antithrombin III is a 58kDa glycoprotein synthesized in the liver. It has two domains, a heparin-binding domain and target protease binding domain. |
| Immunogen: | human antithrombin III |
| Physical form: | Lyophilized from 0.01 M phosphate buffered saline, pH 7.2 |
| Reconstitution: | Reconstitute with 2 mL deionized water. |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 41 |
| Safety Statements | 26-39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |