N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide
SIGMA/A9968 - ≥95%
Synonym: Ac-IETD-pNA
Empirical Formula (Hill Notation): C27H38N6O12
Molecular Weight: 638.62
MDL Number: MFCD01318840
Linear Formula: C27H38N6O12
Product Type: Chemical
assay | ≥95% |
form | powder |
InChI | 1S/C27H38N6O12/c1-5-13(2) |
InChI key | FHURKTIGZAIQGR-BQCLNCLCSA |
Quality Level | 200 |
SMILES string | CC[C@H](C)[C@H](NC(C)=O)C |
storage temp. | −20°C |
Amino Acid Sequence: | NAc-Ile-Glu-Thr-Asp-pNA |
Application: | Chromogenic substrate for caspase 8 and granzyme B. |
Biochem/physiol Actions: | IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3. |
Packaging: | 5 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% |
Storage Temp. | −20°C |
UNSPSC | 12352209 |