Anti-YWHAQ antibody produced in rabbit
SIGMA/AV02062 - affinity isolated antibody
Synonym: Anti-1C5; Anti-HS1
Product Type: Chemical
Immunohistochemistry Anti-YWHAQ: Cat. No. AV02062: Immunohistochemistry of YWHAQ in Human Kidney tissue with YWHAQ antibody at 4-8 μg/mL.
Immunoblotting Cell Type: SW620 (Cat. No. AV02062). Lanes 1. Antibody dilution (concentration) 1.0 μg/mL in cell type SW620
Western Blotting Western Blot of YWHAQ in Mouse Kidney with YWHAQ antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 28 kDa |
| NCBI accession no. | NP_006817   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat, guinea pig, dog, bovine |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P27348 |
| Application: | Anti-YWHAQ antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable. |
| Biochem/physiol Actions: | YWHAQ is a regulator of intrinsic apoptotic pathway. Promoter variation of YWHAQ gene reduces cell death and affects the treatment outcomes in childhood acute lymphoblastic leukemia. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human YWHAQ |
| Other Notes: | Synthetic peptide located within the following region: SVAYKNVVGGRRSAWRVISSIEQKT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |