Anti-CDK8 antibody produced in rabbit
SIGMA/AV03050 - IgG fraction of antiserum
Synonym: Anti-
MDL Number: MFCD02262687
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 53 kDa |
NCBI accession no. | NP_001251 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | rabbit, bovine, dog, human, mouse, pig, horse |
storage temp. | −20°C |
technique(s) | western blot: suitable |
UniProt accession no. | P49336 |
Application: | Anti-CDK8 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml. |
Biochem/physiol Actions: | CDK8 is a regulator of transcription in a multisubunit complex with TFIIH and TEF-β. It exerts positive and negative effects on transcription and is involved signaling that controls nutrient sensing and cell differentiation. CDK8 phosphorylates the regulatory serine residue of STAT1 and mediates JAK-STAT1 signaling. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human CDK8 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: GLIMTSDYQRSNPHAAYPNPGPSTS |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |