Anti-CXCL3 antibody produced in rabbit
SIGMA/AV07037 - IgG fraction of antiserum
Synonym: Anti-CINC-2b; Anti-GRO3; Anti-GROg; Anti-MIP-2b; Anti-MIP2B; Anti-SCYB3
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 11 kDa |
NCBI accession no. | NP_002081 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | western blot: suitable |
UniProt accession no. | P19876 |
Application: | Anti-CXCL3 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. |
Biochem/physiol Actions: | CXCL3 is a chemokine that binds to CXCR1 and CXCR2 receptors and stimulates p38 and ERK1/2-dependent migration of asthmatic airway smooth muscle cells. Prostate stromal cells secrete CXCL3 in response to IL-1 that results in prostatic inflammation in early stages of prostate cancer formation. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the middle region of human CXCL3 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: QSVNVRSPGPHCAQTEVIATLKNGK |
Target description: | CXCL3 is a chemokine that affects migration and adhesion of monocytes. CXCR2 is its known receptor. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |