Anti-HSP90AB1 antibody produced in rabbit
SIGMA/AV09016 - IgG fraction of antiserum
Synonym: Anti-Heat shock protein 90 kDa α (cytosolic), class B member 1
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of HSP90AB1 in Human heart with HSP90AB1 antibody at 4-8 μg/mL
Immunoblotting Cell Type: HepG2 (Cat. No. AV09016). Lanes 1. Antibody dilution (concentration) 0.625 μg/mL in cell type HepG2
Western Blotting Western Blot of HSP90AB1 in Mouse Skeletal Muscle with HSP90AB1 antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 83 kDa |
| NCBI accession no. | NP_031381   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, guinea pig, goat, bovine, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P08238 |
| Biochem/physiol Actions: | HSP90AB1 (heat shock protein 90kDa α (cytosolic), class B member 1) is a molecular chaperone that mediates protein folding and intracellular trafficking. It interacts with important oncoproteins such as MET, Akt, p53 and Raf-1 kinase and modulates the signaling pathway that results in cell proliferation and survival. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human HSP90AB1 |
| Other Notes: | Synthetic peptide located within the following region: MPEEVHHGEEEVETFAFQAEIAQLM |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |