Anti-CAV3 antibody produced in rabbit
SIGMA/AV09021 - affinity isolated antibody
Synonym: Anti-Caveolin 3
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of CAV3 in Human placental with CAV3 antibody at 4-8 μg/mL
Immunoblotting Cell Type: fetal skeletal muscle (Cat. No. AV09021). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal skeletal muscle
Western Blotting Western Blot of CAV3 in Human placenta with CAV3 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 17 kDa |
| NCBI accession no. | NP_203123   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P56539 |
| Application: | Anti-CAV3 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml. |
| Biochem/physiol Actions: | Caveolin-3 is a membrane protein that binds to the Ca(2+)-release channel, RyR1 and facilitates caveolae formation and Ca+2 homeostasis. CAV3 regulates human ether-a-go-go-related gene (hERG) channels that controls cardiac repolarization. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human CAV3 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: MMAEEHTDLEAQIVKDIHCKEIDLV |
| Target description: | CAV-3 is a meber of the caveolin family of proteins. It functions as a scaffolding protein caveolin-interacting components and is found highly expressed in muscle. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |