Anti-BCL2A1 antibody produced in rabbit
SIGMA/AV09047 - affinity isolated antibody
Synonym: Anti-BCL2-related protein A1
Product Type: Chemical
Immunoblotting Cell Type: MW Marker & Jurkat (Cat. No. AV09047). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type MW Marker 2. Antibody dilution (concentration) 1 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 20 kDa |
| NCBI accession no. | NP_004040   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| Application: | Anti- BCL2A1 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. |
| Biochem/physiol Actions: | The expression of BCL2A1 protein is regulated by NF-κB transcription factor. It has prosurvival and metastatic effects and facilitates survival of leukocytes subsets and inflammation. It is upregulated in melanomas and chronic inflammatory diseases. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | BCL2 proteins are important regulators of cell death and survival. They are recognized as cellular oncogenes that are often deregulated in cancers. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human BCL2A1 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: FIMNNTGEWIRQNGGWENGFVKKFE |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |