Anti-CHRNB2 antibody produced in rabbit
SIGMA/AV13020 - affinity isolated antibody
Synonym: Anti-Cholinergic receptor, nicotinic, β 2 (neuronal)
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 57 kDa |
NCBI accession no. | NP_000739 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | bovine, pig, human, mouse, dog |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | western blot: suitable |
UniProt accession no. | P17787 |
Application: | Anti-CHRNB2 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. |
Biochem/physiol Actions: | CHRNB2 is a transmembrane, oligomeric, ligand-gated nicotinic receptor that induces ion channel opening for the movement of positive ions when it is activated by cholinergic binding. Nicotinic acetylcholine receptors mediate presynaptic, postsynaptic and extrasynaptic signaling. Mutations in gene that codes for CHRNB2 have been observed in autosomal dominant nocturnal frontal lobe epilepsy and memory deficits. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the N terminal region of human CHRNB2 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: SGVWGTDTEERLVEHLLDPSRYNKL |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |