Anti-PDPK1 antibody produced in rabbit
SIGMA/AV30313 - affinity isolated antibody
Synonym: Anti-
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV30313). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 63 kDa |
| NCBI accession no. | XP_001715356   |
| shipped in | wet ice |
| species reactivity | bovine, horse, dog, rabbit, human, mouse, guinea pig, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | O15530 |
| Application: | Rabbit Anti-PDPK1 antibody has been used for western blot assays at a concentration of 0.5μg/ml. |
| Biochem/physiol Actions: | PDPK1 phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. It may play a general role in signaling processes and in development. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | PDPK1 is a kinase that regulates several signaling pathways mediated by various hormones and growth factors. PDPK1 has been implicated in breast cancer metastasis and prostate cancer progression. Rabbit Anti-PDPK1 antibody recognizes human, mouse, rat, zebrafish, and pig PDPK1. |
| Immunogen: | Synthetic peptide directed towards the middle region of human PDPK1 |
| Other Notes: | Synthetic peptide located within the following region: IIHRDLKPENILLNEDMHIQITDFG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |