Anti-CEBPB antibody produced in rabbit
SIGMA/AV31259 - affinity isolated antibody
Synonym: Anti-CCAAT/enhancer binding protein (C/EBP), β
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of CEBPB in Human Appendix (Colon) with CEBPB antibody at 4-8 μg/mL
Immunoblotting Cell Type: HepG2 (Cat. No. AV31259). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type HepG2
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 36 kDa |
| NCBI accession no. | NP_005185   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, guinea pig, human, bovine |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | P17676 |
| Application: | Rabbit Anti-CEBPB antibody can be used for western blot applications at 0.5μg/ml. |
| Biochem/physiol Actions: | The protein encoded by this intronless gene, CEBPB, is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | CEBPB is a hepatic transcription factor that contains the basic leucine zipper (bZIP) domain. This transcription factor is known to interact with genes involved in acute phase response, metabolic activities, homeostatic functions, and the progression of cell cycle. Rabbit Anti-CEBPB antibody binds to bovine, human, and pig CEBPB. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human CEBPB |
| Other Notes: | Synthetic peptide located within the following region: ADAKAPPTACYAGAAPAPSQVKSKA |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |