Anti-KLF1 antibody produced in rabbit
SIGMA/AV31493 - affinity isolated antibody
Synonym: Anti-EKLF; Anti-Kruppel-like factor 1 (erythroid)
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV31493). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 38 kDa |
| NCBI accession no. | NP_006554   |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q13351 |
| Application: | Rabbit Anti-KLF1 antibody can be used for western blot assays at 1μg/ml. |
| Biochem/physiol Actions: | KLF1 is a transcription factor, originally identified in this laboratory, which plays a crucial role as a transcriptional activator at the adult beta-globin locus. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | KFL1 is known to modulate BCL11A expression and can increase human γ-globin/β-globin expression ratios. Furthermore, KFL1 haploinsufficiency can cause hereditary persistence of fetal hemoglobin. Rabbit Anti-KLF1 antibody recognizes bovine, pig, human, mouse, and rat KLF1. |
| Immunogen: | Synthetic peptide directed towards the middle region of human KLF1 |
| Other Notes: | Synthetic peptide located within the following region: PKALALQPVYPGPGAGSSGGYFPRT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |