Anti-RAX (AB2) antibody produced in rabbit
SIGMA/AV31926 - affinity isolated antibody
Synonym: Anti-RX; Anti-Retina and anterior neural fold homeobox
Product Type: Chemical
Immunohistochemistry Anti-RAX (ab2): Cat. No. AV31926: Immunohistochemistry of RAX in Human Spermatophore tissue with RAX antibody at 4-8 μg/mL.
Immunoblotting Cell Type: MCF7 (Cat. No. AV31926). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type MCF7
Western Blotting Western Blot of RAX in Human Fetal Lung with RAX antibody at 1 μg/mL
Western Blotting Western Blot of RAX in Human 293T Whole Cell with RAX antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 37 kDa |
| NCBI accession no. | NP_038463   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, mouse, human, guinea pig, bovine, rat |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9Y2V3 |
| Application: | Rabbit Anti-RAX (AB2) antibody can be used for western blot assays at a concentration of 0.5μg/ml. |
| Application: | Rabbit polyclonal anti-RAX (AB2) antibody is used to tag retina and anterior neural fold homeobox for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of retina and anterior neural fold homeobox in eye field/retinal development and eye pathologies such as microphthalmia and anophthalmia. |
| Biochem/physiol Actions: | Retinal Homeobox Protein Rx (RAX) is a member of homeobox family of transcription factors. Mutations mouse and fish RAX lead to defects in retinal development and result in animal models of anophthalmia. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Rabbit polyclonal anti-RAX (AB2) antibody reacts with bovine, canine, human, mouse, and rat retina and anterior neural fold homeobox factors. |
| General description: | Retina and anterior neural fold homeobox (RAX) is a paired-type homeobox gene expressed in the anterior neural fold and developing retina. RAX is involved in defining the eye field during early development wherein it participates in regulation of the proliferation and/or differentiation of retinal cells. Defects in RAX have been linked to the eye pathologies microphthalmia and anophthalmia. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human RAX |
| Other Notes: | Synthetic peptide located within the following region: MHLPGCAPAMADGSFSLAGHLLRSP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |