Anti-PBX2 (AB2) antibody produced in rabbit
SIGMA/AV32069 - affinity isolated antibody
Synonym: Anti-G17; Anti-HOX12; Anti-PBX2MHC; Anti-Pre-B-cell leukemia homeobox 2
Product Type: Chemical
Immunoblotting Cell Type: transfected 293T (Cat. No. AV32069). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type transfected 293T
Western Blotting Western Blot of PBX2 in Mouse Pancreas with PBX2 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 46 kDa |
| NCBI accession no. | NP_002577   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, guinea pig, horse, mouse, rat |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | P40425 |
| Application: | Rabbit Anti-PBX2 (AB2) antibody can be used for western blot applications at a concentration of 0.5μg/ml. |
| Biochem/physiol Actions: | PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | PBX2 is a homeobox transcription factor that shares homology with the human proto-oncogene, PBX1. Studies have reported that PBX2 forms triple complexes with HOXA9 and MEIS1 in myeloid cells. Rabbit Anti-PBX2 (AB2) antibody recognizes pig, human, mouse, and rat PBX2. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human PBX2 |
| Other Notes: | Synthetic peptide located within the following region: MDERLLGPPPPGGGRGGLGLVSGEP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |