Anti-EGR1 antibody produced in rabbit
SIGMA/AV32241 - affinity isolated antibody
Synonym: Anti-AT225; Anti-Early growth response 1; Anti-G0S30; Anti-KROX-24; Anti-NGFI-A; Anti-TIS8; Anti-ZIF-268; Anti-ZNF225
Product Type: Chemical
Immunohistochemistry Anti-EGR1: Cat. No. AV32241: Immunohistochemistry of EGR1 in Human Intestine tissue with EGR1 antibody at 4-8 μg/mL.
Immunohistochemistry Anti-EGR1: Cat. No. AV32241: Immunohistochemistry of EGR1 in Human Spleen tissue with EGR1 antibody at 4-8 μg/mL.
Immunohistochemistry Anti-EGR1: Cat. No. AV32241: Immunohistochemistry of EGR1 in Colon, myenteric plexus tissue with EGR1 antibody at 5.0 μg/mL.
Immunoblotting Cell Type: fetal lung (Cat. No. AV32241). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal lung
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 57 kDa |
| NCBI accession no. | NP_001955   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P18146 |
| Application: | Rabbit polyclonal anti-EGR1 antibody is used to tag early growth response 1 factor for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of early growth response 1 factor in cell processes such as apoptosis, differentiation, mitogenesis and senescence. |
| Biochem/physiol Actions: | Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human EGR1 |
| Other Notes: | Synthetic peptide located within the following region: DNYPKLEEMMLLSNGAPQFLGAAGA |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |