Anti-FOXL1 antibody produced in rabbit
SIGMA/AV32303 - IgG fraction of antiserum
Synonym: Anti-Forkhead box L1
Product Type: Chemical
Immunohistochemistry Anti-FOXL1: Cat. No. AV32303: Immunohistochemistry of FOXL1 in Human Muscle tissue with FOXL1 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: liver (Cat. No. AV32303). Lanes 1. Antibody dilution (concentration) 2.5 μg/mL in cell type liver
Western Blotting Western Blot of FOXL1 in Mouse Skeletal Muscle with FOXL1 antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 36 kDa |
| NCBI accession no. | NP_005241   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, horse, human, pig, dog |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q12952 |
| Application: | Rabbit Anti-FOXL1 antibody can be used for western blot (2.5μg/ml) and IHC (4-8μg/ml) assays. |
| Biochem/physiol Actions: | FOXL1 is a member of the forkhead family. The forkhead domain is a monomeric DNA binding motif that defines a rapidly growing family of eukaryotic transcriptional regulators. Genetic and biochemical data suggest a central role in embryonic development for forkhead proteins. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The Forkhead Box L1 (FoxL1) is a transcription factor that modulates epithelial growth and gastrointestinal development. This transcription factor has been implicated in pancreatic and gastrointestinal carcinogenesis and can also function as prognostic biomarker for clear cell renal cell carcinoma. Studies in mce have also revealed that FoxL1 can function as a biological marker of the hepatic progenitor cells. Rabbit Anti-FOXL1 antibody recognizes canine, human, and mouse FOXL1. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human FOXL1 |
| Other Notes: | Synthetic peptide located within the following region: HLFDPRLPALAASPMLYLYGPERPG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |