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Anti-RUVBL1 antibody produced in rabbit

SIGMA/AV32349 - affinity isolated antibody

Synonym: Anti-ECP54; Anti-NMP238; Anti-Pontin52; Anti-RVB1; Anti-RuvB-like 1 (E. coli); Anti-TIH1; Anti-TIP49; Anti-TIP49A

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-AV32349-100UL 100 µL
$541.00
1/EA
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Immunohistochemistry RUVBL1 Antibody: Cat. No. AV32349: Immunohistochemistry analysis of RUVBL1 in Human Heart with RUVBL1 Antibody Antibody Concentration: 4.0-8.0 μg/mL. Cellular Data: cardiac cell of renal tubule
Immunoblotting Cell Type: fetal heart (Cat. No. AV32349). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal heart
Immunoblotting RUVBL1: Cat. No. AV32349: Western blot analysis of RUVBL1 in Human Fetal Lung cell lysates with RUVBL1 antibody at 1.0 μg/mL.

 

antibody form affinity isolated antibody
antibody product type primary antibodies
biological source rabbit
clone polyclonal
concentration 0.5 mg - 1 mg/mL
conjugate unconjugated
form buffered aqueous solution
mol wt 50 kDa
NCBI accession no. NP_003698 
Quality Level 100 
shipped in wet ice
species reactivity dog, bovine, mouse, human, horse, rabbit, rat, guinea pig
storage temp. −20°C
technique(s) western blot: suitable
UniProt accession no. Q9Y265 
Application: Rabbit Anti-RUVBL1 antibody can be used for western blot applications at a concentration of 1μg/ml.
Biochem/physiol Actions: RUVBL1 (RuvB-like AAA ATPase 1) is involved in various cellular processes including transcriptional regulation, DNA replication, DNA damage repair, chromatin remodeling and apoptosis. In the chromatin-remodeling process, it conjugates with other proteins to form the human histone acetylase/chromatin-remodeling complex TIP60, which plays an essential role in transcription and DNA repair. The chromatin-remodeling complex regulates chromatin structure as well as it maintains DNA-based export in the cell. It also functions as a component of the human RNA polymerase II holoenzyme complex, which indicates its role in transcriptional processes. RUVBL1 is also associated with two oncogenic pathways, c-Myc and another, β-catenin pathways. In addition, it also performs in small nucleolar ribonucleoprotein particle assembly, nucleolar localization, and trafficking.
Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description: Rabbit Anti-RUVBL1 antibody recognizes zebrafish, human, mouse, rat, chicken, canine, and bovine RUVBL1.
Immunogen: Synthetic peptide directed towards the N terminal region of human RUVBL1
Other Notes: Synthetic peptide located within the following region: KIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGV
Physical form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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