Anti-TLE3 antibody produced in rabbit
SIGMA/AV32362 - IgG fraction of antiserum
Synonym: Anti-Transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
Product Type: Chemical
Immunoblotting Cell Type: HepG2 (Cat. No. AV32362). Lanes 1. Antibody dilution (concentration) 2.5 μg/mL in cell type HepG2
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 83 kDa |
| NCBI accession no. | NP_005069   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | pig, dog, human, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q04726 |
| Application: | Rabbit Anti-TLE3 antibody can be used for western blot applications at a concentration of 2.5μg/ml. |
| Biochem/physiol Actions: | The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | TLE3 is known to function as a transcriptional coregulator of adipogenesis. It interacts with HESX1 and PROP1 to regulate transcriptional expression. Rabbit Anti-TLE3 antibody recognizes human, zebrafish, rat, mouse, and canine TLE3. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human TLE3 |
| Other Notes: | Synthetic peptide located within the following region: GSSSGLLALGALGSQAHLTVKDEKN |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |