Anti-OTX2 antibody produced in rabbit
SIGMA/AV32439 - affinity isolated antibody
Synonym: Anti-Orthodenticle homeobox 2
Product Type: Chemical
Immunohistochemistry Anti-OTX2: Cat. No. AV32439: Immunohistochemistry of OTX2 in Human Stomach tissue with OTX2 antibody at 4-8 μg/mL.
Immunohistochemistry Anti-OTX2: Cat. No. AV32439: Immunohistochemistry of OTX2 in Human Stomach tissue with OTX2 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV32439). Lanes 1. Antibody dilution (concentration) 1.0-10.0 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 32 kDa |
| NCBI accession no. | NP_068374   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, bovine, dog, guinea pig, horse, rabbit, sheep, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P32243-2 |
| Application: | Rabbit Anti-OTX2 antibody can be used for western blot applications at a concentration of 1.0-10.0μg/ml. It can also be used for IHC applications at 4-8μg/ml. |
| Biochem/physiol Actions: | Homeobox protein OTX2 is a member of the bicoid sub-family of homeodomain-containing transcription factors. This protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined. This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | OTX2 is a homeodomain transcription factor that regulates organ development. Studies in mice have shown that Otx2 is involved in determining the fate of retinal photoreceptor cells. This transcription factor has also been implicated in pineal gland development. Rabbit Anti-OTX2 antibody recognizes canine, chicken, human, mouse, rat, rabbit, zebrafish, and bovine OTX2. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human OTX2 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: PESRVQVWFKNRRAKCRQQQQQQQN |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |