Anti-KLF8 (AB2) antibody produced in rabbit
SIGMA/AV32859 - affinity isolated antibody
Synonym: Anti-Kruppel-like factor 8
Product Type: Chemical
Immunoblotting Cell Type: HepG2 (Cat. No. AV32859). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type HepG2
Western Blotting Western Blot of KLF8 in Mouse Kidney with KLF8 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 39 kDa |
| NCBI accession no. | NP_009181   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, dog |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | O95600 |
| Application: | Rabbit Anti-KLF8 (AB2) antibody can be used for western blot applications at a concentration of 0.5μg/ml. It has also been used for immunohistochemistry applications. |
| Biochem/physiol Actions: | KLF8 is abnormally expressed in female patients with X autosome translocation t(X;21)(p11.2;q22.3) and non-syndromic mental retardation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | KLF8 functions as a downstream target of focal adhesion kinase (FAK) during cell cycle progression and cyclin D1 regulation. It has also been implicated in oncogenic transformation. Furthermore, KLF8 is known to have prognostic implications in gastric adenocarcinomas. Rabbit Anti-KLF8 (AB2) antibody recognizes human, mouse, and rat KLF8. |
| Immunogen: | Synthetic peptide directed towards the middle region of human KLF8 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: LEIPSDSEESTIESGSSALQSLQGL |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |