Anti-MMP9 antibody produced in rabbit
SIGMA/AV33090 - IgG fraction of antiserum
Product Type: Chemical
Immunohistochemistry Anti-MMP9: Cat. No. AV33090: Immunohistochemistry of MMP9 in Rat and Mouse tissue with MMP9 antibody at 2-15 μg/mL.
Immunoblotting Cell Type: K562 (Cat. No. AV33090). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type K562
Western Blotting Western Blot of MMP9 in Human Fetal Lung with MMP9 antibody at 1 μg/mL
Western Blotting Western Blot of MMP9 in Human Ovary Tumor with MMP9 antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 78 kDa |
| NCBI accession no. | NP_004985   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, dog, mouse, guinea pig, horse, bovine, sheep, rat, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P14780 |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Application: | Rabbit polyclonal anti-MMP9 antibody is used to tag matrix metalloproteinase-9/gelat |
| Biochem/physiol Actions: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Matrix metalloproteinase-9/gelat |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human MMP9 |
| Other Notes: | Synthetic peptide located within the following region: VAEHGDGYPFDGKDGLLAHAFPPGP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |