Anti-SOX17 antibody produced in rabbit
SIGMA/AV33271 - affinity isolated antibody
Synonym: Anti-SRY (sex determining region Y)-box 17
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 44 kDa |
NCBI accession no. | NP_071899 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human, pig, dog |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | western blot: suitable |
UniProt accession no. | Q9H6I2 |
Biochem/physiol Actions: | The SOX17 gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | SRY-box (SOX) transcription factors bind the minor groove of DNA to modulate gene expression. SRY-box 17 (SOX17) regulates a variety of developmental processes such as endoderm formation. SOX17 is an antagonist to Wnt/β-catenin pathway cell signaling. SOX17 is a potential biomarker for breast cancer carcinogenesis and progression. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human SOX17 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: GTDPSQPAELLGEVDRTEFEQYLHF |
Specificity: | Rabbit polyclonal anti-SOX17 antibody reacts with canine, human, and pig SRY (sex determining region Y)-box 17 transcription factors. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |