Anti-TCF21 antibody produced in rabbit
SIGMA/AV33421 - affinity isolated antibody
Synonym: Anti-Transcription factor 21
Product Type: Chemical
Immunohistochemistry Anti-TCF21: Cat. No. AV33421: Immunohistochemistry of TCF21 in Human Brain, cortex, senile plaque tissue with TCF21 antibody at 5.0 μg/mL.
Immunoblotting Cell Type: fetal lung (Cat. No. AV33421). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal lung
Western Blotting Western Blot of TCF21 in Human HeLa with TCF21 antibody at 1 μg/mL
Western Blotting Western Blot of TCF21 in Human 293T Whole Cell with TCF21 antibody at 1 μg/mL
Western Blotting Western Blot of TCF21 in Human Ovary Tumor with TCF21 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 20 kDa |
| NCBI accession no. | NP_003197   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, rabbit, mouse, rat, human, dog, guinea pig, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | O43680 |
| Biochem/physiol Actions: | The TCF21 gene encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | TCF-21 is a mesoderm specific basic-helix-loop-helix transcription factor. It forms a dimer with TCF-3 and binds to Ebox motifs to initiate transcription. It is a 19 kDa protein and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human TCF21 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: SNCENGSPQKGRGGLGKRRKAPTKK |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |