Anti-CLDN17 antibody produced in rabbit
SIGMA/AV33615 - IgG fraction of antiserum
Synonym: Anti-Claudin 17
Product Type: Chemical
Immunohistochemistry Anti-CLDN17: Cat. No. AV33615: Immunohistochemistry of CLDN17 in Human Lung tissue with CLDN17 antibody at 4-8 μg/mL.
Immunohistochemistry Anti-CLDN17: Cat. No. AV33615: Immunohistochemistry of CLDN17 in Human Lung tissue with CLDN17 antibody at 4-8 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 25 kDa |
| NCBI accession no. | NP_036263   |
| shipped in | wet ice |
| species reactivity | rat, mouse, human, dog, pig, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P56750 |
| Biochem/physiol Actions: | CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-1 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | CLDN17 is a member of the claudin family of proteins. It is a component of tight-junction strands that serve as physical barriers to prevent movement of solutes between the layers of epithelial and endothelial cells. Recently, CLDN17 was shown to have increased expression in breast cancer compared to normal breast tissue. |
| Immunogen: | Synthetic peptide directed towards the middle region of human CLDN17 |
| Other Notes: | Synthetic peptide located within the following region: KQVQCTGSNERAKAYLLGTSGVLFI |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |