Anti-GTF2IRD1 (AB1) antibody produced in rabbit
SIGMA/AV33735 - IgG fraction of antiserum
Synonym: Anti-CREAM1; Anti-GTF2I repeat domain containing 1; Anti-GTF3; Anti-MUSTRD1; Anti-RBAP2; Anti-WBSCR11; Anti-WBSCR12; Anti-hMusTRD1α1
Product Type: Chemical
Immunohistochemistry Anti-GTF2IRD1 (ab1): Cat. No. AV33735: Immunohistochemistry of GTF2IRD1 in Human Kidney tissue with GTF2IRD1 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: transfected 293T (Cat. No. AV33735). Lanes 1. Antibody dilution (concentration) 2.5 μg/mL in cell type transfected 293T
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 106 kDa |
| NCBI accession no. | NP_005676   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rabbit, bovine, guinea pig, mouse, rat, horse, human, dog |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9UHL9 |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Chromatin immunoprecipitation (1 paper) Immunocytochemistry (1 paper) Western Blotting (1 paper) |
| Biochem/physiol Actions: | GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. GTF2IRD1 is related to Williams-Beuren syndrome, a multisystem developmental disorder. Western blots using three different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human GTF2IRD1 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: TFGSQNLERILAVADKIKFTVTRPF |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |