Anti-C4BPB antibody produced in rabbit
SIGMA/AV33814 - affinity isolated antibody
Synonym: Anti-Complement component 4 binding protein, β
Product Type: Chemical
Immunohistochemistry Anti-C4BPB: Cat. No. AV33814: Immunohistochemistry of C4BPB in Human Kidney tissue with C4BPB antibody at 4-8 μg/mL.
Immunoblotting Cell Type: fetal liver (Cat. No. AV33814). Lanes 1. Antibody dilution (concentration) 1.0 μg/mL in cell type fetal liver
Immunoblotting C4BPB: Cat. No. AV33814: Western blot analysis of C4BPB in Human 721_B cell lysates with C4BPB antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 28 kDa |
| NCBI accession no. | NP_000707   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P20851 |
| Biochem/physiol Actions: | C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human C4BPB |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: CCLMVAWRVSASDAEHCPELPPVDN |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |