Anti-RRN3 (AB1) antibody produced in rabbit
SIGMA/AV34462 - affinity isolated antibody
Synonym: Anti-RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV34462). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 74 kDa |
| NCBI accession no. | NP_060897   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | yeast, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9NYV6 |
| Biochem/physiol Actions: | RRN3 is RNA polymerase I-specific transcription initiation factor. Phosphorylation of RRN3 by MAPK cascades links cell signaling with the control of gene expression, namely results in rRNA synthesis in turn cell growth.. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | RRN3 is conserved between yeast and humans. It is required for transcription initiation by RNA polymerase 1 where it assists in formation of the preinitiation complex. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human RRN3 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: KKDIVEDEDDDFLKGEVPQNDTVIG |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |