Anti-METTL3 (AB1) antibody produced in rabbit
SIGMA/AV34590 - IgG fraction of antiserum
Synonym: Anti-
Product Type: Chemical
Immunoblotting Cell Type: Raji (Cat. No. AV34590). Lanes 1. Antibody dilution (concentration) 5 μg/mL in cell type Raji
Western Blotting Western Blot of METTL3 in Human HepG2 with METTL3 antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 64 kDa |
| NCBI accession no. | NP_062826   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, human, bovine, goat, mouse, horse, rat, rabbit, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q86U44 |
| Application: | Rabbit Anti-METTL3 antibody is suitable for western blot applications at a concentration of 5 μg/ml. |
| Biochem/physiol Actions: | METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransf |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Methyltransferase like 3 (METTL3 or M6A) codes for a 70 kDa subunit of MT-A. This protein forms a heterodimeric complex with METTL14 and modulates the methylation of the mammalian nuclear RNA, N6-adenosine. Rabbit Anti-METTL3 antibody recognizes bovine, human, mouse, rat, zebrafish, and canine METTL3. |
| Immunogen: | Synthetic peptide directed towards the middle region of human METTL3 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: AKEPAKKSRKHAASDVDLEIESLLN |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |